Primary Complex

A primary complex (PC) is a localised lesion formed due to the reaction of the body tissues to the first exposure to tubercle bacilli. The lung is the most frequent site of primary infection. Inhaled bacilli get implanted in the periphery of the lung where a "tubercle" is formed. Initially the response consists of an accumulation of polymorphs, followed by macrophages and 4-6 weeks later lymphocytes appear in large numbers. The bacilli also spread to the draining hilar lymph nodes where the same changes occur. The lesion at the point of entry and that in the node together form the primary complex

Agriculture, food security, nutrition and the Millennium Development Goals

"...Today, 1.1 billion people live on less than one US dollar per day (the internationally recognized poverty threshold)—430 million in South Asia, 325 million in Sub-Saharan Africa, 260 million in East Asia and the Pacific, and 55 million in Latin America. Too many children live lives characterized by hunger and illness, and all too often succumb to early death. Moreover, another 1.6 billion people live on between one and two dollars per day, often sliding temporarily below the one dollar per day threshold. To enable all these people to live in dignity, the eight goals to achieve by 2015 are: 1. Eradicate extreme poverty and hunger 2. Achieve universal primary education 3. Promote gender equality and empower women 4. Reduce child mortality 5. Improve maternal health 6. Combat HIV/AIDS, malaria, and other diseases 7. Ensure environmental sustainability 8. Develop a global partnership for development." from TextMillenium Development Goals ,HIV/AIDS ,Gender issues ,Equality ,Nutrition ,Impact ,

The nutrition transition in India

No Abstract.South African Journal of Clinical Nutrition Vol. 18(2) 2005: 198-20

Induced corssing over in Drosophila males by ethyl methane sulphonate

This article does not have an abstract

On tuning passive black-box macromodels of LTI systems via adaptive weighting

This paper discusses various approaches for tuning the accuracy of rational macromodels obtained via black-box identification or approximation of sampled frequency responses of some unknown Linear and Time-Invariant system. Main emphasis is on embedding into the model extraction process some information on the nominal terminations that will be connected to the model during normal operation, so that the corresponding accuracy is optimized. This goal is achieved through an optimization based on a suitably defined cost function, which embeds frequency-dependent weights that are adaptively refined during the model construction. A similar procedure is applied in a postprocessing step for enforcing model passivity. The advantages of proposed algorithm are illustrated on a few application examples related to power distribution networks in electronic system

Sero Diagnosis of Tuberculosis in Children Using Two ELISA Kits

The diagnosis of childhood tuberculosis is based on circumstantial evidence in the absence of a gold standard in the majority of cases. Sero-diagnosis offers scope for an early diagnosis in a variety of clinical conditions and is simple to perform. A number of mycobacterial antigens have been used for antibody detection assays and several are available as kits in the market. This study was done to evaluate the value of antibody detection kits (ELISA) against the A60 antigen and 38kDa antigen of Mycobacterium tuberculosis in the diagnosis of childhood tuberculosis at the outpatient department of the Institute of Social Paediatrics, Government Stanley Hospital in collaboration with Tuberculosis Research Centre, Chennai. Thirty five children with pulmonary tuberculosis, 7 with TB lymphadenitis and 22 healthy controls were studied. In addition to routine investigations including gastric lavage for AFB culture, serum antibodies against the A60 and 38kDa antigens were assayed using commercially available ELISA kits. With A60, IgM serum levels were positive in 74% of pulmonary TB cases, 57% of TB lymphadenitis cases and 50% of controls. A60 IgG was positive in 17% of pulmonary TB, 86% of TB lymphadenitis and 14% of controls. The 38 kDa IgG antibody was positive in 37% of pulmonary and 86% of TB lymphadenitis cases and 27% of controls. Among 10 culture confirmed cases, A60 IgM was positive in 8, A60 IgG in 3 and 38kDa IgG in 5 patients. The sensitivity of the tests ranged between 29% and 71% and specificity between 50% and 86%. Although the numbers are small, the results suggest that serodiagnosis using the currently available antigens of M. tuberculosis is unlikely to be a confirmatory test for tuberculosis in children